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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0664 All Species: 20.61
Human Site: S731 Identified Species: 37.78
UniProt: O75153 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75153 NP_056044.3 1309 146670 S731 P G V R F P E S C Q D E V R D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548323 1501 166268 S923 P G V R F P E S C Q E E V R D
Cat Felis silvestris
Mouse Mus musculus Q5SW19 1315 148050 S733 P G V R F P E S C Q D E V R D
Rat Rattus norvegicus XP_001080615 1352 151608 S774 P G V R F P E S C Q D E V R D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509391 982 108607 H465 R L G F P R P H R H K L C C L
Chicken Gallus gallus XP_415920 1293 145294 S766 P G V R F P E S S R E E V Q D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A0JMD0 1400 155792 D841 P G V R F P D D S N D D I K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAB5 1448 160833 G834 P G I R H A D G E E G T S L A
Honey Bee Apis mellifera XP_624898 1290 145677 P743 P G V K H P D P N G P A L K K
Nematode Worm Caenorhab. elegans P34466 1247 139903 T711 S N V K H A P T E N L E R Q R
Sea Urchin Strong. purpuratus XP_001198284 1101 124381 S584 E E I E I Y S S I E C K G I K
Poplar Tree Populus trichocarpa XP_002314020 1343 146561 N686 E I A A D E E N V K K V G S Y
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RY84 1211 135142 D646 E M A Q D E Q D V R D A C T Y
Conservation
Percent
Protein Identity: 100 N.A. N.A. 83.3 N.A. 94.9 89.9 N.A. 60.8 83.1 N.A. 75 N.A. 52 59.8 39.9 51.9
Protein Similarity: 100 N.A. N.A. 85.5 N.A. 96.9 92.7 N.A. 67.2 89.3 N.A. 83.6 N.A. 69 75.7 59.5 63.7
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 100 100 N.A. 0 73.3 N.A. 46.6 N.A. 20 26.6 13.3 6.6
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 0 93.3 N.A. 73.3 N.A. 40 53.3 33.3 26.6
Percent
Protein Identity: 27.3 N.A. N.A. N.A. N.A. 29
Protein Similarity: 46.6 N.A. N.A. N.A. N.A. 48.9
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 20 N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 8 0 16 0 0 0 0 0 16 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 31 0 8 0 16 8 0 % C
% Asp: 0 0 0 0 16 0 24 16 0 0 39 8 0 0 39 % D
% Glu: 24 8 0 8 0 16 47 0 16 16 16 47 0 0 0 % E
% Phe: 0 0 0 8 47 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 62 8 0 0 0 0 8 0 8 8 0 16 0 0 % G
% His: 0 0 0 0 24 0 0 8 0 8 0 0 0 0 0 % H
% Ile: 0 8 16 0 8 0 0 0 8 0 0 0 8 8 0 % I
% Lys: 0 0 0 16 0 0 0 0 0 8 16 8 0 16 24 % K
% Leu: 0 8 0 0 0 0 0 0 0 0 8 8 8 8 8 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 8 8 16 0 0 0 0 0 % N
% Pro: 62 0 0 0 8 54 16 8 0 0 8 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 8 0 0 31 0 0 0 16 0 % Q
% Arg: 8 0 0 54 0 8 0 0 8 16 0 0 8 31 8 % R
% Ser: 8 0 0 0 0 0 8 47 16 0 0 0 8 8 0 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 0 8 0 8 0 % T
% Val: 0 0 62 0 0 0 0 0 16 0 0 8 39 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _